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I am currently performing researches in Max Planck Institute as a bioinformatics PhD student. I have almost-none background in biology but a very long-term experience in software engineering (more than 2 decades). This is one of the best courses that I've ever taken. Especially, this course provide a challenging but interesting exercises, assignments and detailed text as well as video lectures. The text and pseudo codes are sometimes unclear. Some assignment do not have sufficient amount of testing data sets and their expected output or the grader would not work as you expected. However, you could overcome such problems by taking a look at the discussion board.