Molecular Evolution (Bioinformatics IV)

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Molecular Evolution (Bioinformatics IV)

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FREE,
Add a Verified Certificate for $79

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Coursera online courses
Coursera's online classes are designed to help students achieve mastery over course material. Some of the best professors in the world - like neurobiology professor and author Peggy Mason from the University of Chicago, and computer science professor and Folding@Home director Vijay Pande - will supplement your knowledge through video lectures. They will also provide challenging assessments, interactive exercises during each lesson, and the opportunity to use a mobile app to keep up with yo...
Coursera's online classes are designed to help students achieve mastery over course material. Some of the best professors in the world - like neurobiology professor and author Peggy Mason from the University of Chicago, and computer science professor and Folding@Home director Vijay Pande - will supplement your knowledge through video lectures. They will also provide challenging assessments, interactive exercises during each lesson, and the opportunity to use a mobile app to keep up with your coursework. Coursera also partners with the US State Department to create “learning hubs” around the world. Students can get internet access, take courses, and participate in weekly in-person study groups to make learning even more collaborative. Begin your journey into the mysteries of the human brain by taking courses in neuroscience. Learn how to navigate the data infrastructures that multinational corporations use when you discover the world of data analysis. Follow one of Coursera’s “Skill Tracks”. Or try any one of its more than 560 available courses to help you achieve your academic and professional goals.

Provider Subject Specialization
Humanities
Sciences & Technology
4694 reviews

Course Description

In the previous course in the Specialization, we learned how to compare genes, proteins, and genomes. One way we can use these methods is in order to construct a "Tree of Life" showing how a large collection of related organisms have evolved over time. In the first half of the course, we will discuss approaches for evolutionary tree construction that have been the subject of some of the most cited scientific papers of all time, and show how they can resolve quandaries from finding the origin of a deadly virus to locating the birthplace of modern humans. In the second half of the course, we will shift gears and examine the old claim that birds evolved from dinosaurs. How can we prove this? In particular, we will examine a result that claimed that peptides harvested from a T. rex fossil closely matched peptides found in chickens. In particular, we will use methods from computational proteomics to ask how we could assess whether th... In the previous course in the Specialization, we learned how to compare genes, proteins, and genomes. One way we can use these methods is in order to construct a "Tree of Life" showing how a large collection of related organisms have evolved over time. In the first half of the course, we will discuss approaches for evolutionary tree construction that have been the subject of some of the most cited scientific papers of all time, and show how they can resolve quandaries from finding the origin of a deadly virus to locating the birthplace of modern humans. In the second half of the course, we will shift gears and examine the old claim that birds evolved from dinosaurs. How can we prove this? In particular, we will examine a result that claimed that peptides harvested from a T. rex fossil closely matched peptides found in chickens. In particular, we will use methods from computational proteomics to ask how we could assess whether this result is valid or due to some form of contamination. Finally, you will learn how to apply popular bioinformatics software tools to reconstruct an evolutionary tree of ebolaviruses and identify the source of the recent Ebola epidemic that caused global headlines.
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