Medicinal Chemistry: The Molecular Basis of Drug Discovery

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10/10 stars
based on  13 reviews
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Medicinal Chemistry: The Molecular Basis of Drug Discovery

Course Details

Cost

FREE

Upcoming Schedule

  • Upcoming

Course Provider

edX online courses
Harvard University, the Massachusetts Institute of Technology, and the University of California, Berkeley, are just some of the schools that you have at your fingertips with edX. Through massive open online courses (MOOCs) from the world's best universities, you can develop your knowledge in literature, math, history, food and nutrition, and more. These online classes are taught by highly-regarded experts in the field. If you take a class on computer science through Harvard, you may be tau...
Harvard University, the Massachusetts Institute of Technology, and the University of California, Berkeley, are just some of the schools that you have at your fingertips with edX. Through massive open online courses (MOOCs) from the world's best universities, you can develop your knowledge in literature, math, history, food and nutrition, and more. These online classes are taught by highly-regarded experts in the field. If you take a class on computer science through Harvard, you may be taught by David J. Malan, a senior lecturer on computer science at Harvard University for the School of Engineering and Applied Sciences. But there's not just one professor - you have access to the entire teaching staff, allowing you to receive feedback on assignments straight from the experts. Pursue a Verified Certificate to document your achievements and use your coursework for job and school applications, promotions, and more. EdX also works with top universities to conduct research, allowing them to learn more about learning. Using their findings, edX is able to provide students with the best and most effective courses, constantly enhancing the student experience.

Provider Subject Specialization
Sciences & Technology
Business & Management
24035 reviews

Course Description

This medicinal chemistry course explores how chemists modify a molecule’s structure to design a safe and effective drug.

This course opens with a brief history of drug discovery and introduces the modern drug approval process. Then, we will transition to learning about receptors and enzymes, the body’s molecules most often targeted by drugs. We will also discuss the topics of pharmacokinetics (drug adsorption, elimination, and half-life) and metabolism. The course closes with units on how potential drug molecules are identified and subsequently optimized into safe and effective drugs.

Reviews 10/10 stars
13 Reviews for Medicinal Chemistry: The Molecular Basis of Drug Discovery

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Rankings are based on a provider's overall CourseTalk score, which takes into account both average rating and number of ratings. Stars round to the nearest half.

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David Moses profile image
David Moses profile image

David Moses

10/10 starsCompleted
4 years, 11 months ago
A fascinating topic covered in a multifaceted way by a masterful and friendly teacher. Aside from basic medicinal chemistry and pharmacokinetics, the course also includes some history, some experience with online tools such as molecule-drawing software and protein and drug databases, and some insight into the drug discovery process including a number of interesting interviews with industry professionals. The class is very well organized, with each unit containing a short lecture (accompanied by a neat summary in PDF format) followed by some text that goes into a bit more depth than the lecture and then an assignment that forces one to practice what one has just learned. Professor Stevens’s lecture style is clear and engaging, and one thing that sets this class apart from the general run of online classes is how nice he is about answering questions on the discussion boards. Regarding the level, one needs some experience with or at lea... A fascinating topic covered in a multifaceted way by a masterful and friendly teacher. Aside from basic medicinal chemistry and pharmacokinetics, the course also includes some history, some experience with online tools such as molecule-drawing software and protein and drug databases, and some insight into the drug discovery process including a number of interesting interviews with industry professionals. The class is very well organized, with each unit containing a short lecture (accompanied by a neat summary in PDF format) followed by some text that goes into a bit more depth than the lecture and then an assignment that forces one to practice what one has just learned. Professor Stevens’s lecture style is clear and engaging, and one thing that sets this class apart from the general run of online classes is how nice he is about answering questions on the discussion boards. Regarding the level, one needs some experience with or at least some interest in chemistry to do the assignments, but I think that anyone with an interest in drug discovery can profit from watching the lectures and the interviews.
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Praveen Kumar profile image
Praveen Kumar profile image

Praveen Kumar

10/10 starsTaking Now
5 years ago
Prof Erland Stevens is one of the most dedicated fellows I met. He answers how much ever doubt I ask mostly in less than 2 hours. Excellent course.
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Sarah Smith profile image
Sarah Smith profile image

Sarah Smith

10/10 starsTaking Now
5 years ago
They give exams online? How it works? I want to take the course but a need to know hor is the methods they use for evaluating students.
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Student

10/10 starsCompleted
5 years, 4 months ago
This is an amazing course for a beginner. It gives a practical overall exposure to the subject. I am eagerly waiting to take this course one more time as well as an advanced topic, preferably from the same Instructor.
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eric mooc profile image
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eric mooc

10/10 starsCompleted
5 years, 4 months ago
Excellent ! Superb ! Can't wait for session II. Pr Stevens please !... Teach us more ! This has been my best on Edx so far
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Carlos P. Roca profile image
Carlos P. Roca profile image
10/10 starsCompleted
  • 6 reviews
  • 6 completed
5 years, 8 months ago
This is an amazing course for anyone with an interest in chemistry or with curiosity about pharmaceuticals and their effects on the body. The design of the course is first-class, with a very well planned sequence of lectures, examples and exercises. The course covers quite an amount of non-trivial material, without being overwhelming. I found the examples highly interesting and up-to-date. The interviews with experts working in each chapter's topics are a very nice complement, specially for those considering a career in the pharma industry.
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Gesiane Pajarinen profile image
Gesiane Pajarinen profile image
10/10 starsCompleted
  • 3 reviews
  • 3 completed
5 years, 10 months ago
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Steven Frank profile image
Steven Frank profile image
10/10 starsCompleted
  • 59 reviews
  • 57 completed
5 years, 3 months ago
This was the best chemistry course I’ve ever taken, and I majored in chemistry. One reason is that, although there are plenty of reactions and kinetics, the course is really an exploration of how chemistry serves the process of discovering, optimizing, and ultimately marketing drugs. So Professor Stevens first takes you through the basic business and regulatory framework of the pharmaceutical industry – clinical trials, the FDA, how drugs are protected by intellectual property. The course then covers the basics of pharmacokinetics: what drugs actually do, how the body absorbs, distributes, metabolizes and ultimately eliminates them – and how drug designers use dosing regimens and molecular design to obtain efficacy without harming the patient. From there you dive more deeply into the chemistry of binding and metabolism, and then into the mechanics of drug discovery – the use of automation, combinatorial chemistry and targ... This was the best chemistry course I’ve ever taken, and I majored in chemistry. One reason is that, although there are plenty of reactions and kinetics, the course is really an exploration of how chemistry serves the process of discovering, optimizing, and ultimately marketing drugs. So Professor Stevens first takes you through the basic business and regulatory framework of the pharmaceutical industry – clinical trials, the FDA, how drugs are protected by intellectual property. The course then covers the basics of pharmacokinetics: what drugs actually do, how the body absorbs, distributes, metabolizes and ultimately eliminates them – and how drug designers use dosing regimens and molecular design to obtain efficacy without harming the patient. From there you dive more deeply into the chemistry of binding and metabolism, and then into the mechanics of drug discovery – the use of automation, combinatorial chemistry and targeting strategies to find needles in the vast haystack of potential molecules that constitutes “drug space.” One aspect of this course that makes it so enjoyable is the way case studies and anecdotes are used to illustrate key class topics. The need for regulation is exemplified by discussion of mass poisonings that have occurred as a result of drug contamination, for example, and to learn how drug candidates are identified and optimized, we follow the trail of Abbott researchers as they develop stromelysin inhibitors to treat arthritis and cancer. The chemistry topics often involve familiar pharmaceutical names – Viagra, Ibuprofen, and Tamiflu all make appearances, adding a level of relevance often missing from courses that dig into the hard science. Professor Stevens is a marvelous teacher. His superb command of the material is no surprise, but he knows exactly where his students may get confused and how to pre-empt that confusion. He is quick with clever, illuminating analogies and visual illustrations, and the lectures are always engaging, never boring. Also, his level of dedication to this course, actively monitoring the discussion board and answering questions personally, was truly heroic. If you have a decent chemistry background and even a passing interest in the world of pharma, you will love this class.
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student

10/10 starsCompleted
6 years, 6 months ago
Just amazing. Very unconventional and interesting approach as compared to subjects taught at the university.
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student

10/10 starsCompleted
6 years, 5 months ago
Absolutely fantastic course! This course has made me fall in love with a subject I used to despise. I had only hazy memories of first-year chem, which I almost failed about 15 years ago, but that was enough to allow me to follow the course. I have learned so much, but more importantly I now have a real passion for the subject. I would recommend this course to anyone with even a passing interest in pharmacology.
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student

10/10 starsCompleted
6 years, 5 months ago
The teaching was very good, the availability and helpfulness of the professor unparalleled, the difficulty level adequate - not too low so that one would feel like not having accomplished anything noteworthy, not too difficult and not too mired in details. I now feel very comfortable explaining to people who don't know about this subject the basics of drug development, and I'm also able to go into enough detail to have a meaningful discussion with people in the medical field. I can recommend this course wholeheartedly.
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student

10/10 starsCompleted
6 years, 5 months ago
Gracias!!! He aprendido muchisimo gracias a este curso. Ojala pudieran certificarme siendo Audit. Desde Colombia.
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Keep it private profile image
Keep it private profile image
10/10 starsCompleted
  • 1 review
  • 1 completed
6 years, 6 months ago
I currently have high school background in chemistry, and I found this course extremely interesting. It's well organized, professor Erland Stevens is a very good, communicative lecturer. I would recommend this course to anyone interested in chemistry, especially organic chemistry. The lecture videos are accompanied by external articles that are usually very interesting, and may give deeper understanding of the topic.
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Rankings are based on a provider's overall CourseTalk score, which takes into account both average rating and number of ratings. Stars round to the nearest half.