Principles of Biochemistry

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FREE,
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edX online courses
Harvard University, the Massachusetts Institute of Technology, and the University of California, Berkeley, are just some of the schools that you have at your fingertips with edX. Through massive open online courses (MOOCs) from the world's best universities, you can develop your knowledge in literature, math, history, food and nutrition, and more. These online classes are taught by highly-regarded experts in the field. If you take a class on computer science through Harvard, you may be tau...
Harvard University, the Massachusetts Institute of Technology, and the University of California, Berkeley, are just some of the schools that you have at your fingertips with edX. Through massive open online courses (MOOCs) from the world's best universities, you can develop your knowledge in literature, math, history, food and nutrition, and more. These online classes are taught by highly-regarded experts in the field. If you take a class on computer science through Harvard, you may be taught by David J. Malan, a senior lecturer on computer science at Harvard University for the School of Engineering and Applied Sciences. But there's not just one professor - you have access to the entire teaching staff, allowing you to receive feedback on assignments straight from the experts. Pursue a Verified Certificate to document your achievements and use your coursework for job and school applications, promotions, and more. EdX also works with top universities to conduct research, allowing them to learn more about learning. Using their findings, edX is able to provide students with the best and most effective courses, constantly enhancing the student experience.

Provider Subject Specialization
Sciences & Technology
Business & Management
22215 reviews

Course Description

Principles of Biochemistry integrates an introduction to the structure of macromolecules and a biochemical approach to cellular function. Topics addressing protein function will include enzyme kinetics, the characterization of major metabolic pathways and their interconnection into tightly regulated networks, and the manipulation of enzymes and pathways with mutations or drugs. An exploration of simple cells (red blood cells) to more complex tissues (muscle and liver) will be used as a framework to discuss the progression in metabolic complexity. Learners will also develop problem solving and analytical skills that are more generally applicable to the life sciences.

New in version 2, learners will explore how alteration of these metabolic pathways relates to the development and progression of some human diseases.


HarvardX requires individuals who enroll in its courses on edX to abide by the terms of the edX honor code. H...

Principles of Biochemistry integrates an introduction to the structure of macromolecules and a biochemical approach to cellular function. Topics addressing protein function will include enzyme kinetics, the characterization of major metabolic pathways and their interconnection into tightly regulated networks, and the manipulation of enzymes and pathways with mutations or drugs. An exploration of simple cells (red blood cells) to more complex tissues (muscle and liver) will be used as a framework to discuss the progression in metabolic complexity. Learners will also develop problem solving and analytical skills that are more generally applicable to the life sciences.

New in version 2, learners will explore how alteration of these metabolic pathways relates to the development and progression of some human diseases.


HarvardX requires individuals who enroll in its courses on edX to abide by the terms of the edX honor code. HarvardX will take appropriate corrective action in response to violations of the edX honor code, which may include dismissal from the HarvardX course; revocation of any certificates received for the HarvardX course; or other remedies as circumstances warrant. No refunds will be issued in the case of corrective action for such violations. Enrollees who are taking HarvardX courses as part of another program will also be governed by the academic policies of those programs.

HarvardX pursues the science of learning. By registering as an online learner in an HX course, you will also participate in research about learning. Read our research statement to learn more.

Harvard University and HarvardX are committed to maintaining a safe and healthy educational and work environment in which no member of the community is excluded from participation in, denied the benefits of, or subjected to discrimination or harassment in our program. All members of the HarvardX community are expected to abide by Harvard policies on nondiscrimination, including sexual harassment, and the edX Terms of Service. If you have any questions or concerns, please contact harvardx@harvard.edu and/or report your experience through the edX contact form.

Image credit: PDB ID 2DN1, 2DN2

Park S-Y, Yokoyama T, Shibayama N, Shiro Y, Tame JRH (2006) 1.25 A resolution crystal structures of human haemoglobin in the oxy, deoxy and carbonmonoxy forms. J Mol Biol 360: 690–701.

Reviews 10/10 stars
15 Reviews for Principles of Biochemistry

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Rankings are based on a provider's overall CourseTalk score, which takes into account both average rating and number of ratings. Stars round to the nearest half.

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Student

10/10 starsCompleted
3 years, 7 months ago
MCB63X is a huge course, it took three months of daily effort to get through it all. But as a software developer with no formal background in biology, the resulting knowledge is certainly empowering. I look at food differently now, for example (and vitamins, fasting, prescription drugs, chemotherapy, cyanide, diabetes, sore muscles, etc, etc). Huge kudos to Dr. Viel and Dr. Gaudet for the fantastic lectures and for taking the time to put this class together--also for having such a great sense of humor (and glasses) throughout. Kudos too for the generosity of the staff and TAs for their timely responses to our questions. This class is a remarkable offering. I hope this crew will put together another class on this topic. I'll be there if they do!
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sandeep tiwari profile image
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sandeep tiwari

10/10 starsDropped
2 years ago
i think ur organisation making us fool because i cant find any course which one is free for me and its jusr waste of time
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Barry Adwal profile image
Barry Adwal profile image

Barry Adwal

10/10 starsDropped
2 years, 11 months ago
Nice Course, the only sad part is that the verified option is closed. It would be really great if the verified option is reopened...
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Davey J profile image
Davey J profile image

Davey J

10/10 starsCompleted
2 years, 11 months ago
The content is excellent. I use this course as a supplement for reviewing my MCAT exam. The introductory bioenergetics background information, along with some chemistry background (e.g., molecular orbitals) were helpful indeed. The contents are organized in a logical fashion. Essential elements of biochem -- macromolecular structures/functions and cell metabolism are covered in-depth. The questions that come along with the lectures are exceptional. They really helped me rethink about the concepts learned. Lecture notes were offered as PDFs in high resolution (they are great resource for making your own study sheets and flashcards) The course also incorporates exercises of PyMOL, which sets this course apart from all biochem classes that I have formally taken in school.
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Jenny C profile image
Jenny C profile image
10/10 starsCompleted
  • 1 review
  • 1 completed
2 years, 11 months ago
Best online course I have done. Very challenging and took a long time to complete (over 3 months) but I really felt I was being give an in-depth introduction to biochemistry. I have no formal background in biology, so it took much longer each week than was advertised, but that is to be expected. Excellent instructors. I would recommend to others.
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Nandha Kumar E profile image
Nandha Kumar E profile image

Nandha Kumar E

10/10 starsTaking Now
3 years ago
Great teaching from Alan and Rachel.High quality materials.Best online course for Biochemistry ever. Would recommend this to anyone to study or review the topics in Biochem.
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George Zafiris profile image
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George Zafiris

10/10 starsCompleted
3 years, 2 months ago
MCB63X was a challenging and yet a very rewarding course. I strongly recommend it if you're about to dive into a case study or you're just a lover of the subject. Every second of every lecture and exercise you'll do will help you undestand and lose any doubts or fears you may have for biochemistry. The instructors are helpful and they know how to properly stimulate your effort in a way that benefits you! I'm a software engineer with no formal experience on the subject. Dive into it!
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student

8/10 starsCompleted
3 years, 5 months ago
This review is totally honest and objective. CONTENT: Very good INSTRUCTOR AND METHODOLOGY: A very mixed bag. Instructor knowledge was very good. The methodology was poor. The instructor just read from what obviously was a written text. That wasn't instructing... it was reading. In this fashion, any person who could read well could teach the course in the same way and with the "same skills". There was no instructor interaction with the course slides/diagrams. What was also a problem was that the instructor speaks English with a rather strong French accent, which makes it difficult to understand him. Consistently the instructor places word accents on the wrong syllables and begins sentences with high volume and usually ends them with a low-volume mumble. I was expecting a much better course delivery methodology and skills from a Harvard University course. In summary, I am glad that I took the course. Thank you for offering it. I will ... This review is totally honest and objective. CONTENT: Very good INSTRUCTOR AND METHODOLOGY: A very mixed bag. Instructor knowledge was very good. The methodology was poor. The instructor just read from what obviously was a written text. That wasn't instructing... it was reading. In this fashion, any person who could read well could teach the course in the same way and with the "same skills". There was no instructor interaction with the course slides/diagrams. What was also a problem was that the instructor speaks English with a rather strong French accent, which makes it difficult to understand him. Consistently the instructor places word accents on the wrong syllables and begins sentences with high volume and usually ends them with a low-volume mumble. I was expecting a much better course delivery methodology and skills from a Harvard University course. In summary, I am glad that I took the course. Thank you for offering it. I will definitely try other courses. I strongly recommend edx.org to anyone that wants to learn and also wants to be a life-long learner.
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David Moses profile image
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David Moses

10/10 starsCompleted
3 years, 6 months ago
This is a wonderful course. The instructors cover a huge amount of material in a meticulous but friendly way. The quizzes that follow each video are perfect for a quick review of what was just discussed, and the extra-credit assignments go beyond the basics in interesting ways. Professor Viel, who does the great majority of the lectures, clearly has a great deal of teaching experience. He takes a somewhat cyclical approach such that the most central items (such as the path of glycolysis) are covered in many different sections, reviewing and adding on new material each time. Putting this course together obviously involved a great deal of work for the instructors and staff; I hope that many students will enjoy the fruits of their labor.
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Student

10/10 starsTaking Now
3 years, 6 months ago
By far and away the best online course I have taken. This was not a dummied down intro to course but provided great insight and understanding of basic human biochemistry for layman. However presented in a very clear and understandable manner for a layman. I would love to see a follow up course to this!
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Rex Outtrim profile image
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Rex Outtrim

10/10 starsCompleted
3 years, 9 months ago
This was an excellent course and experience. It provides essential and complex topics that allow for review and enlightenment in current concepts. It requires rigorous note taking and attention to details in order to do well on the quizzes. The format is awesome and it allows the experience of having a 'private tutor' in biochemistry. Pause, repeat, review with or without closed-captioning.
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Dave Acker profile image
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Dave Acker

10/10 starsCompleted
3 years, 10 months ago
Absolutely amazing course! Covers much more than I had in high school biology, such as protein folding, membrane specific metabolism and nucleotide synthesis, and has made me consider majoring in biochemistry in college. Some of the content was difficult so I only recommend this course to those who have had at least some exposure to the material.
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Philip Jang profile image
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Philip Jang

10/10 starsCompleted
3 years, 11 months ago
The course offers a great understanding of biochemistry and the downloadable pdfs and the clear-cut slides offer a clear demonstration of the underlying principles. Additionally, Professor Viel offers a great understanding through his clear-cut straightforward method of explaining things. Finally, Harvard has provided a great course that will most certainly offer a great learning experience. Another thing is that this course is hard but work hard and you will do well.
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Adam Emord profile image
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Adam Emord

10/10 starsTaking Now
3 years, 11 months ago
rigorous, thought-provoking and fun
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Tingting Zhao profile image
Tingting Zhao profile image

Tingting Zhao

10/10 starsCompleted
3 years, 11 months ago
Best course ever, 10 out of 5!
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